Home

This is a picture of me standing in front of Buckeye Grove and the Horseshoe on Ohio State's campus. I graduated from Freed-Hardeman in December of 2003 with a B.S. in biology. I completed my Ph.D. in molecular, cellular, and developmental biology at The Ohio State University in June of 2010. The focus of my dissertation research was to characterize extracellular and intracellular regulation of DNA repair machinery.

I have always loved studying biology. Studying biology helps you understand more about the world around you, more about yourself and how you work, and ultimately, more about the mind and power of The Creator. I have found that studying biology has had a profound impact on my faith as I have grown in my appreciation for what God did in Genesis and how He continues to sustain life.

Curriculum Vita

Education

The Ohio State University             Ph.D.          Molecular, Cellular, &          June 2010
Columbus, OH                                               Developmental Biology

Freed-Hardeman                         B.S.            Biology                               December 2003
University Henderson, TN


Dissertation Title:
“Characterization of Novel Extracellular and Intracellular Modifiers of Apurinic/Apyrimidinic Endonuclease 1”

Teaching Experience

The Ohio State University           Graduate Teaching Associate, College of Pharmacy
Columbus, OH


The Ohio State University           Graduate Teaching Associate, College of Medicine
Columbus, OH

Other Experience

PROFESSIONAL PUBLICATIONS

Publications

Huang, H, Liu, T, Rose, JL, Stevens, RL, Hoyt, DG: Sensitivity of mice to lipopolysaccharide is
increased by a high saturated fat and cholesterol diet. Journal of Inflammation, 4:22, 2007.

Abstracts

Huang, H, Rose, JL, Stevens, RL, Hoyt, DG: Effects of antioxidants on endotoxin and
interferongamma-induced nitric oxide and hydrogen peroxide production in mouse aortic
endothelial cells FASEB Journal, 18(5): A1002, 2004.

Huang, H, Stevens RL, Hoyt, DG: High-fat diet synergizes with endotoxin and interferon-
gamma to induce pro-inflammatory gene expression in various murine tissues in vivo. FASEB
Journal, 19(4):A777, 2005.

Stevens, RL, Okoreeh, A, Hoyt, DG: Fibroblast Growth Factor-2 inhibits bleomycin-induced
DNA damage in murine lung endothelial cells. FASEB Journal, 20(4): A673, 2006.

Schneider, R, Stevens, RL, Hoyt, DG: Soluble anti-beta1 integrin antibody induces
phosphorylation of focal adhesion kinase and protein kinase B/AKT in mouse aortic endothelial
cells FASEB Journal, 21(5), 2007.

Stevens, RL, Okoreeh, A, Hoyt, DG: Effects of bleomycin and integrin engagement on physical
DNA breakage in endothelial cells. FASEB Journal, 21(5): A754, 2007.

Stevens, RL and Hoyt, DG: Integrin engagement reduces APE1 co-immunoprecipitation with
XRCC1 in hydrogen peroxide-treated murine lung endothelial cells. FASEB Journal, 22: 777.2,
A130, 2008.

Hoyt, DG, Stevens, RL, Schneider, RA: Effects of synthetic disintegrins on breast cancer
in mice. Era of Hope Proceedings, p. 102, 2008.

Stevens, RL, Schneider, RA, Liu, T, Keshvara L, and Hoyt, DG: APE1 protein levels are
increased in PIN1 depleted murine mammary tumors. FASEB Journal, 23: 927.2, B319, 2009.

Stevens, RL, Schneider, RA, Liu, T, and Hoyt, DG: Depletion of PIN1 increases APE1 activity
in EMT6 murine mammary adenocarcinoma cells. FASEB Journal, submitted, 2010.

PROFESSIONAL PRESENTATIONS

Seminar: Role of Integrin-linked Kinase in Regulating Phosphorylation of Akt and Fibroblast
Survival in Type I Collagen Matrices through a β1 Integrin Viability Signaling Pathway. MCDB 2nd year
literature-based seminar, The Ohio State University, 2006.

Poster Presentation: Fibroblast Growth Factor-2 inhibits bleomycin-induced DNA damage in
murine lung endothelial cells, Experimental Biology Meeting San Francisco, CA, 2006.
Seminar: The Role of Integrins in Response to DNA Damage. MCDB 3rd year research
seminar, The Ohio State University, 2007.

Poster Presentation: Effects of bleomycin and integrin engagement on physical DNA breakage
in endothelial cells, Experimental Biology Meeting, Washington D.C., 2007.

Poster Presentation: Integrin engagement reduces APE1 co-immunoprecipitation with XRCC1
in hydrogen peroxide-treated murine lung endothelial cells, Experimental Biology Meeting, San
Diego, CA; College of Pharmacy Research Day, The Ohio State University; Molecular Life Sciences
Interdisciplinary Graduate Program Symposium, The Ohio State University, 2008.

Poster Presentation: APE1 protein levels are increased in PIN1 depleted murine mammary
tumors, College of Pharmacy Research Day, The Ohio State University; Molecular Life Sciences
Interdisciplinary Graduate Program Symposium, The Ohio State University, 2009.

Poster Presentation: Depletion of PIN1 increases APE1 activity in EMT6 murine mammary
adenocarcinoma cells, College of Pharmacy Research Day, The Ohio State University; Molecular Life
Scienes Interdisciplinary Graduate Program Symposium, The Ohio State University, 2010.

Exit Seminar: Characterization of a Novel Intracellular Modifier of APE1, The Ohio State University,
2010.

PROFESSIONAL ORGANIZATIONS

2006-present Society for Pharmacology and Experimental Therapeutics (ASPET)
2009-2010 American Medical Writers Association (AMWA)
2009-2010 BioOhio

PROFESSIONAL CONFERENCES

Experimental Biology Meeting San Francisco, CA 2006

Experimental Biology Meeting Washington D.C. 2007

Experimental Biology Meeting San Diego, CA 2008